How deactivating an inhibitor causes absence epilepsy: validation of a noble lie.
نویسنده
چکیده
منابع مشابه
مروری بر صرع کوچک با رویکرد به علوم پایه
Abstract Background: Epilepsy is one of the most common neurological disorders. Seizures could be presented as general or focal attacks. Absence epilepsy is one of the main forms of the general epilepsy and associated with sudden impairment of consciousness and non/convulsive generalized attacks. The prevalence of absence epilepsy was estimated about 10% of all types of seizures and seizures o...
متن کاملP 145: A Review of Animal Models of Absence Epilepsy
The most common type of childhood-onset epilepsy syndrome is childhood absence epilepsy (CAE) with well-defined electro clinical features but unknown pathological basis. The incidence of absence epilepsy is about 2 and 8 out of every 100 000 children up to the age of 16, and the prevalence is 2 and 10% of children with any form of epilepsy. Children with CAE suffer from high rate of pretreatmen...
متن کاملDipeptidyl peptidase-4 inhibitor ameliorates status epilepticus seizures and cognitive disturbances in a rat model of temporal lobe epilepsy
Background and Objective: In temporal lobe epilepsy (TLE), recurrent seizures accompany with cognitive deficit. In some patients, the current medications cannot provide satisfactory control of seizures, therefore new drugs that act through different mechanisms are required. In the present study, the useful effect of dipeptidyl peptidase-4 inhibitor was evaluated in experimental model of tempora...
متن کاملبررسی میزان شیوع صرع در ایران به روش مرور سیستماتیک و متاآنالیز
Background and Objective: Epilepsy is a one of the most common diseases causing many problems in Iran. Hence, this study was an attempt to assess the prevalence of epilepsy using meta-analysis and systematic review methods in Iran. Materials and Methods: Nine Iranian papers published in time period of 2002 to 2010 were selected using valid keywords and searching in the SID, Google scholar, PubM...
متن کاملExperimental Models of Absence Epilepsy; A Review Article
Background: Absence epilepsy is a brief non-convulsive seizure that associated with sudden abrupt in consciousness. Because of the unpredictable occurrence of absence seizures and ethic limitation of human investigation on the pathogenesis and drug assessment led to the tendency to animal models. The aim of this paper is reviewing the advantages and disadvantages of several animal models of non...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Epilepsy currents
دوره 13 1 شماره
صفحات -
تاریخ انتشار 2013